Drug treatment which interacts with or blocks synthesis of specific cellular components, to impede the biochemical dysfunction involved in progression of the disease.
Intervention: The phase II trial assessed vascular endothelial growth factor- targetedtherapy±Srcinhibition.
2
However, the clinical translation of molecular-guided targetedtherapy is hampered by challenges.
3
The benefit of HER2- targetedtherapy in this patient population requires further study.
4
Length of stay and mortality were lower in patients receiving targetedtherapy.
5
This in turn identified more patients who are eligible for targetedtherapy.
1
Its therapeutic potential warrants further development for ovarian cancer moleculartargetedtherapy.
2
Novel treatment strategies, including moleculartargetedtherapy, are currently being explored.
3
Activating EGFR mutations were subsequently discovered in 2004, and heralded the era of moleculartargetedtherapy in NSCLC.
4
Purpose of review: This article reviewed the recent developments in moleculartargetedtherapy in head and neck cancers.
5
The relatively high prevalence of positive staining for EGFR supports the use of moleculartargetedtherapy in this disease.
6
Designing moleculartargetedtherapy with high specificity based on novel tumor biomarkers is a high priority in lung cancer research.
7
Several previous studies have found that moleculartargetedtherapy with tyrosine kinase inhibitors is effective against colorectal cancer with elevated SRC expression.
8
These results indicate that IL-11Ra is a potential target for the development of moleculartargetedtherapy and noninvasive tumor imaging in human osteosarcoma.
9
To determine other tumors in which such a moleculartargetedtherapy might be indicated, we investigated KIT expression in different human tumor types.
10
The therapeutic successes achieved are due to advances in neuroimaging, surgical techniques, radiotherapy, and induction of newer chemotherapeutic agents along with moleculartargetedtherapy.
11
Moleculartargetedtherapy represents a novel therapeutic approach.
12
Moleculartargetedtherapy represents a promising new strategy for treating cancers because many small-molecule inhibitors targeting protein kinases have recently become available.